When He broke the third seal, I heard the third living creature saying, “Come.” I looked, and behold, a black horse; and he who sat on it had a pair of scales in his hand. And I heard something like a voice in the center of the four living creatures saying, “A quart of wheat for a denarius, and three quarts of barley for a denarius; and do not damage the oil and the wine.” –Revelations 6:5-6

Boss Famine
Found In
The Basement

The Cellar
Normal Enemy (Later Floors)

Dropped Items
Ball of Bandages

Cube of Meat

Unlocked By
Defeating Mom for the first time

Famine is a boss that can appear in the Basement or the Cellar. He is one of the four Harbingers, and the horseman of Chapter 1.


Phase 1
•If the player is to the left or right of Famine, he will commence charging across the screen.
•He can also spawn up to two Pooters to assist him during the fight, and he will not spawn any more until one of the two Pooters are killed.

Phase 2
•When Famine takes a sufficient amount of damage, his body and horse will explode into gore while his head remains. Famine's head behaves similarly to a Horf, firing triple shots at the player periodically.

Champion VersionsEdit

Blue: Much more aggressive, though cannot summon Pooters. Will shoot six tears radially and will frequently charge the player regardless if they're near him. In Phase 2 he will shoot out a large amount of tears, akin to Monstro's attack.


  • Famine is one of the Four Horsemen of the Apocalypse mentioned in the Bible.
  • Famine appeared in the original Binding of Isaac.
  • A famine is the scarcity of food over a large area.
    • Which can explain Famine's emaciated appearance.


Bosses Boss Monstro
Basement MonstroGeminiDingleLarry Jr.The Duke of FliesGurglingsFistulaStevenFamine
Cellar Gurdy Jr.PinWidowBlighted OvumThe HauntDingleLarry Jr.The Duke of FliesGurglingsFistulaFamine
The Caves ChubGurdyGurdy Jr.Mega MawMega FattyDark OneC.H.A.D.Pestilence
Catacombs The HollowThe HuskPeepPolycephalusThe Carrion QueenThe WretchedDark OnePestilence
The Depths The CageMonstro IIThe AdversaryThe GateLokiGishWarMom
Necropolis The BloatThe Carrion QueenMask of InfamyThe WretchedThe GateLokiWarMom
The Womb Mr. FredScolexTeratomaMama GurdyThe BloatLokiiDeathConquestMom's HeartIt Lives
Utero BlastocystDaddy Long LegsTeratomaMama GurdyThe BloatLokiiTriachnidDeathConquestMom's HeartIt Lives
Sheol The FallenSatan
Dark Room The LambMega Satan
Cathedral Isaac
The Chest ???Mega Satan
Devil Room Krampus
Angel Room Angel
Levels 1-5/7 The FallenThe Headless Horseman
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