|The Womb and Utero|
Defeating Lokii for the first time unlocks Loki's Horns.
There are two sides to this boss. Both sides act like a normal Loki would, but have different health bars, thus you have to kill them separately. Lokii spawns Red Boom Flies instead of Boom Flies.
- Lokii's name is a pun on the Roman numeral for two, II.